PJ Labs is a small workshop.

Local genomics for macOS.

We build Genome: analyse sequencing data, explore variants and trace your results. Right on your Mac.

Download Genome Explore features
Genome 1.6.0 available Processed locally no telemetry macOS 26 Tahoe
GenomeYour data. Your Mac.
Genome: workflow and analysis on macOS
Choose a workflow. Check its inputs. Follow the analysis.

Start with a file. Follow the evidence.

Prepare your sequencing data, investigate a question and document what the data supports.

Explore all analyses →
  1. 01

    Prepare your data

    Start with a FASTQ pair or an existing BAM/CRAM file. Prepare the data and check its quality before analysis.

  2. 02

    Investigate a question

    Look up an rsID, examine a gene or choose a specialised analysis. Keep coverage and quality in view.

  3. 03

    Document your results

    Bring completed analyses together in a PDF, with sources, quality information and the limits of the available data.

A closer look

One rsID. Straight to your BAM.

Search for rs numbers in your BAM file with Genome. Inspect the genotype together with read support and quality, without exporting a genotype file first.

Read the step-by-step guide
.bamrsID
Reference position↓
GenotypeCoverageQuality
How the search works · schematic

Install with one command

Genome is downloaded, verified and installed in your Applications folder.

curl -fsSL https://pjlabs.dev/install/genome.sh | sh

Also from PJ Labs

Look up. Try out. Read on.

Genome App-Icon

Genome for macOS

Your next step with Genome.

Check the requirements for your files, follow the first-analysis guide or download Genome for your Mac.