Genome app icon

PJ Labs · Genome · Download

Version 1.4.1

Genome for macOS.

One DMG, one native app, local genomics on your Mac. No account, no cloud, no trackers, with a visible SHA-256 checksum and clear installation steps.

Genome workflow screenshot

Release package

Genome 1.4.1 · Apple Silicon

DMG image for macOS 26+. After downloading, you can verify the checksum locally with shasum -a 256 Genome-1.4.1.dmg.

macOS
26.0 or newer
Architecture
Apple Silicon (arm64)
Size
12.58 MB
Build
2026-05-31
SHA-256
22bfa9761917680131231fa88fc8ea6d88ba864fd450e42df79bcfb7333e383f

Installation

  1. 1

    Open the DMG

    Double-click the downloaded image.

  2. 2

    Move to Applications

    Copy Genome.app into the Applications folder and eject the DMG.

  3. 3

    First launch

    If Gatekeeper blocks it: right-click → Open; verify the SHA-256 beforehand.

  4. 4

    Tools & references

    Install tools in the app, pick a Reference Library and check the status.